报告题目:
Trade-off effects in cancer evolution
报告时间:
2023年3月12日(星期日)9:30
报告嘉宾:
梁晗(美国德州大学MD安德森癌症中心)
主办单位:
中国遗传学会进化遗传学分会、遗传资源与进化国家重点实验室
直播通道
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报告人介绍
梁晗
美国德州大学MD安德森癌症中心
报告简介
The trade-off effect is an important concept in evolution. As first suggested by Charles Darwin, compromise is inherent in every adaptation as a trade-off. George Williams further formulated the hypothesis and argued that if a change caused both increased reproduction in early life and aging in later life, then that change would be adaptive in evolution. This concept is critical for understanding the origin of aging diseases such as cancers but has been largely ignored in the field. I will discuss two recent studies based on this concept: one focusing on human-specific enhancers, and the other is about developing novel cancer therapeutic strategies for MYC-driven tumors.
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编辑:吴良秀
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