神经酰胺可能比胆固醇更能预测心血管问题,被部分专家称为“心血管风险的极好预测指标”。虽然医疗界对此并未达成统一意见,但首批用于降低神经酰胺水平的药物即将问世。
指导专家
陈桢玥 上海交通大学医学院附属瑞金医院心内科主任医师
参考文献:
1、Lipids called ceramides may be better predictors of cardiovascular problems than cholesterol. Doctors and pharma are waking up to their potential
https://www.science.org/content/article/straight-heart-mysterious-lipids-may-predict-cardiac-problems-better-cholesterol
2、Principles of bioactive lipid signalling: lessons from sphingolipids
链接:https://www.nature.com/articles/nrm2329
3、Aging Up-Regulates Expression of Inflammatory Mediators in Mouse Adipose Tissue
https://journals.aai.org/jimmunol/article/179/7/4829/38003/Aging-Up-Regulates-Expression-of-Inflammatory
4、Translational aspects of sphingolipid metabolism
https://www.cell.com/trends/molecular-medicine/fulltext/S1471-4914(07)00107-4
来源:医学界
责编:田栋梁
编辑:赵 静
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