近年来，纳米技术在医学领域的应用受到了密切关注，这主要是由于将设计好的材料从实验室有效地转化到临床的过程存在诸多挑战。COVID-19大流行期间使用的mRNA疫苗巩固了过去几十年来对纳米技术支持的医疗保健纳米粒子药物递送材料研究的新兴趣。同时得益于细胞生物学和基因工程的进展，这为下一代生物制剂药物递送发展铺平了道路。在该特刊中，我们突出强调创新研究是如何应对这些类型材料有限的靶向性、低载量和高生产成本等挑战的。
特刊全部文章：
https://pubs.acs.org/page/cmatex/vi/drug-delivery
1
Molecular Engineering of Surface Functional Groups Enabling Clinical Translation of Nanoparticle–Drug Conjugates
Fei Wu, Thomas C. Gardinier, Melik Z. Turker, Feng Chen, Pei-Ming Chen, Aranapakam M. Venkatesan, Vaibhav Patel, Gregory P. Adams, Michelle S. Bradbury, Ulrich B. Wiesner, Geno Germano, and Kai Ma*
Chem. Mater. 2022, 34, 12, 5344-5355
2
Influence of Linkers within Stimuli-Responsive Prodrugs on Cancer Therapy: A Case of Five Doxorubicin Dimer-Based Nanoparticles
Qiang Wang, Chong Wang, Shiyou Li, Yuxuan Xiong, Huimin Wang, Zheng Li, Jiangling Wan, Xiangliang Yang, and Zifu Li*
Chem. Mater. 2022, 34, 5, 2085-2097
3
Degradable Carrier-Free Metal–Phenolic Network Theranostic Agent with Targeted Mitochondrial Damage for Efficient Cancer Theranostics
Yu Wen, Junjiao Hu, Jun Liu*, and Ming Li*
Chem. Mater. 2022, 33, 17, 7089-7099
4
Collagen-Targeted Theranostic Nanosponges for Delivery of the Matrix Metalloproteinase 14 Inhibitor Naphthofluorescein
Ting-Yi Wang, Laken L. Kendrick-Williams, Mei Y. Choy, Kelly A. Gilmore, Thomas Bonnard, Hannah A. Pearce, Lok Soon Law, Iska Carmichael, Stephen H. Cody, Karen Alt, Christoph E. Hagemeyer*, and Eva Harth*
Chem. Mater. 2020, 32, 9, 3707-3714
5
Functional Choline Phosphate Lipids for Enhanced Drug Delivery in Cancer Therapy
Wenliang Wang*, Sangni Jiang, Shengran Li, XinXin Yan, Sanrong Liu*, Xiaobo Mao*, and Xifei Yu*
Chem. Mater. 2021, 33, 2, 774-781
6
All-in-One Molecular Aggregation-Induced Emission Theranostics: Fluorescence Image Guided and Mitochondria Targeted Chemo- and Photodynamic Cancer Cell Ablation
Bing Guo, Min Wu, Qi Shi, Tianjiao Dai, Shidang Xu, Jianwen Jiang, and Bin Liu*
Chem. Mater. 2020, 32, 11, 4681-4691
7
Shielded Silver Nanorods for Bioapplications
Xiaolu Zhuo, Malou Henriksen-Lacey, Dorleta Jimenez de Aberasturi, Ana Sánchez-Iglesias, and Luis M. Liz-Marzán*
Chem. Mater. 2020, 32, 13, 5879-5889
8
Delivery of CRISPR/Cas9 Plasmids by Cationic Gold Nanorods: Impact of the Aspect Ratio on Genome Editing and Treatment of Hepatic Fibrosis
Yuxuan Chen, Xiaohong Chen, Di Wu, Huhu Xin, Desui Chen, Da Li, Hongming Pan, Changxin Zhou, and Yuan Ping*
Chem. Mater. 2021, 33, 1, 81-91
9
Polymeric Nanoparticles Integrated from Discrete Organoplatinum(II) Metallacycle by Stepwise Post-assembly Polymerization for Synergistic Cancer Therapy
Jiong Zhou, Guocan Yu*, Jie Yang, Bingbing Shi, Boyong Ye, Mengbin Wang, Feihe Huang*, and Peter J. Stang*
Chem. Mater. 2020, 32, 11, 4564-4573
阅读Chem. Mater.特刊 “The Future of Healthcare Materials” 全部文章：
https://pubs.acs.org/page/cmatex/vi/drug-delivery
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